Publications

Publications

J. Witten, J. Flint, B. Han, J. Stahan, J. Damjanovic, N. Song, T. Poterba, A.J. Cartagena, A. Hirsch, T. Ni, J. Sohl, A. Wagaman, S. Jaswal (2025). NumSimEX: A Method Using EXX Hydrogen Exchange Mass Spectrometry to Map the Energetics of Protein Folding Landscapes. Protein Sci.
E. Collins, J. Ji, S. Kim, J. Witten, S. Kim, R. Zhu, P. Park, M. Jung, A. Park, R. Manan, A. Rudra, G. Keum, E. Bang, J. Jin, R. Langer, D.G. Anderson, W. Im (2025). Lipid Nanoparticle Database towards structure-function modeling and data-driven design for nucleic acid delivery. Nat Commun.
J. Witten, S. Sharma, R. Das, R. Anderson, D.G. Anderson, R. Langer (2025). Biotechnology in Materials Science: A Storied Past and a Bold Future. MRS Bull.
J. Witten, Y. Shi, E. MacDonald, S. Bartlett, A. Pasupathy, E. Ageely, A. Gordon, A. Lapteva, M. Chen, B. Chen, M. Nakano, I. Jun, R. Langer, D.G. Anderson. Nat Commun, under review
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J. Witten, R. Manan, I. Raji, E. Beyer, S. Bartlett, Y. Tang, M. Ebadi, J. Lei, D. Nguyen, F. Oladimeji, A. Jiang, E. MacDonald, Y. Hu, H. Mughal, A. Self, E. Collins, Z. Yan, J.F. Engelhardt, R. Langer, D.G. Anderson (2024). Artificial intelligence-guided design of lipid nanoparticles for pulmonary gene therapy. Nat Biotechnol.
J. Witten, Y. Hu, R. Langer, D.G. Anderson (2024). Recent advances in nanoparticulate RNA delivery systems. PNAS.
A. Jiang, S. Lathwal, S. Meng, J. Witten, E. Beyer, P. McMullen, Y. Hu, R. Manan, I. Raji, R. Langer, D.G. Anderson (2024). Zwitterionic Polymer-Functionalized Lipid Nanoparticles for the Nebulized Delivery of mRNA. JACS.
A. Gordon, B. Li, J. Witten, H. Nguyen, D.G. Anderson (2024). Inhalable Dry Powders for Lung mRNA Delivery. Adv Healthc Mater.
C.E. Wagner, M. Krupkin, K. Smith-Dupont, C. Wu, N. Bustos, J. Witten, K. Ribbeck (2023). A comparison of the physicochemical properties of native mucus and reconstituted mucin gels. Biomacromolecules.
B. Li, A. Jiang, I. Raji, C. Atyeo, T. Raimondo, A. Gordon, L. Rhym, T. Samad, C. MacIsaac, J. Witten, H. Mughal, T. Chicz, R. McNamara, Y. Xu, S. Bhatia, G. Alter, R. Langer, D. Anderson (2023). Enhancing the immunogenicity of lipid-nanoparticle mRNA vaccines by adjuvanting the ionizable lipid and the mRNA. Nat Biomed Eng.