Jacob Witten, PhD Assistant Professor, Department of Genetics & Genome Sciences
Jacob’s research focuses on integrating AI with novel high-throughput screening approaches to design lipid nanoparticles for gene therapy. He received his PhD in Computational and Systems Biology from MIT and was a postdoctoral fellow with Dr. Daniel Anderson.
Google Scholar | GitHub | jxw1952@case.edu
Peng Ning, PhD
Peng is developing lipid nanoparticles for RNA delivery.
Google Scholar | pxn207@case.edu
Shashi Singh, PhD
Shashi’s research develops scalable platforms for targeted RNA delivery and gene editing by combining nanoparticle engineering with high-throughput screening. He uses self-amplifying RNA and ADAR-mediated editing to achieve efficient, low-dose gene modulation in hard-to-target tissues and explores DNA-encoded library–based multiplexed screening to discover new ASO delivery platforms for modulating RNA splicing. He earned his PhD in RNA Biology and Post-Transcriptional Gene Regulation from Jawaharlal Nehru University (New Delhi, India) and was a postdoctoral fellow with Dr. Joseph Luna at Case Western Reserve University (2022–2026) and at Cleveland Clinic (2019–2022).
Google Scholar | LinkedIn | sxs2904@case.edu
Positions available - see Join page
Contact Dr. Witten if interested in research opportunities